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An unnamed pet chameleon (Johnny Depp), whose only friends are some toys and a dead cricket, becomes accidentally stranded in the Nevada desert. After meeting an armadillo (Alfred Molina) who is seeking the mystical Spirit of the West, he narrowly avoids being eaten by a hawk. The next day, after having a surreal nightmare, he meets the lizard Beans (Isla Fisher), a rancher’s daughter, who takes him to Dirt, a tiny, Old West town populated by desert animals.